Oral cancer remains a significant public health challenge in Gujarat, and is as a prominent regional hotspot for oral malignancies in India. Oral and lip cancers constitute a substantial proportion of the state’s cancer burden, with reports indicating that oral cancers account for approximately 11.28% of all cancer cases in the region, particularly among men. The incidence is considerably higher in males than females, largely due to differences in tobacco consumption, chewing habits, alcohol use, and other lifestyle-related factors.